Friday, June 22, 2012

Philip Morris to Introduce Lower-Risk Cigarettes by 2017 | InvestorPlace

Good news:
 Phillip Morris (NYSE:PM) is working on three cigarettes under its popular Marlboro brand that are intended to be less harmful than traditional cigarettes. A cigarette that heats tobacco instead of burning is ready for clinical testing, the company said.

Philip Morris to Introduce Lower-Risk Cigarettes by 2017 | InvestorPlace

6 comments:

  1. Wasn't there recently a brand called Eclipse put out by RJ Reynolds that also heated the tobacco instead of burning it?

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  2. First, there was the Premier by R.J. Reynolds. Then came the Eclipse from R.J. Reynolds. Around the same time Philip Morris developed the Accord. All three heated rather than burned, albeit with "some" combustion (though very little) involved in the process of vaping/smoking these cigarettes.

    I have only been able to get my hands on an Eclipse. My take on the Eclipse is that it's a brilliant idea that has come really close, but not quite close enough (for me, at least) to be considered satisfying. I do believe that there are some people out there who would actually like the Eclipse as is though.. The problem (other than lack of flavor for me) is that no one has really heard about its existence in the first place, mostly due to the American Cancer Society and other like minded anti-smoker groups that raised hell to make sure that it couldn't be promoted to existing smokers as a harm reduction cigarette.

    A study on the Eclipse:

    -A comparison of in vitro toxicities of cigarette smoke condensate from Eclipse cigarettes and four commercially available ultra low-"tar" cigarettes.-

    http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=historysearch&querykey=4

    "Eclipse is a cigarette that primarily heats rather than burns tobacco. R.J. Reynolds Tobacco Company (RJRT) has previously reported the results of in vitro toxicity studies comparing Eclipse with University of Kentucky 1R5F and 1R4F reference cigarettes. To characterize the differences between Eclipse and very low yielding/ultra low-"tar" (vULT) tobacco-burning cigarettes, RJRT conducted a comparative evaluation of the genotoxicity and cytotoxicity of mainstream cigarette smoke condensate (CSC) from Eclipse and three vULT tobacco-burning cigarettes.."

    "Eclipse is a cigarette that primarily heats rather than burns tobacco. R.J. Reynolds Tobacco Company (RJRT) has previously reported the results of in vitro toxicity studies comparing Eclipse with University of Kentucky 1R5F and 1R4F reference cigarettes. To characterize the differences between Eclipse and very low yielding/ultra low-"tar" (vULT) tobacco-burning cigarettes, RJRT conducted a comparative evaluation of the genotoxicity and cytotoxicity of mainstream cigarette smoke condensate (CSC) from Eclipse and three vULT tobacco-burning cigarettes..

    ..Then the study goes on to compare Eclipse with Now Box cigarettes, which no one really smokes btw, because they taste like air. They're so light in fact, that you can't even taste them. Trust me, I used to smoke Now 100 soft pack (which are just slightly less airy than the box pack) and that was about as light as I could go.

    "On a per cigarette basis, the calculated mutagenicity of Eclipse was higher (P<0.05) than Now 83 Box cigarettes in the FTC and 50/30/2 regimens but lower (P<0.05) in the Massachusetts and Canadian regimens. Eclipse CSC was less (P<0.05) cytotoxic as measured in the neutral red assay (based on EC(50) values-microg TPM/ml media) than the CSC from the four test cigarettes regardless of the regimen used. "

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  3. ...So, in other words....the Eclipse was shown to be less cytotoxic as compared to the types of cigarettes that 99% of smokers smoke. Hence, there is a difference between the Eclipse and the conventional cigarette, but don't tell that to the American Cancer Society (who would rather that we smoke cigarettes with the highest level of carcinogens possible it seems)!

    Here is another interesting study:

    -Comparative study of smoke condensates from 1R4F cigarettes that burn tobacco versus ECLIPSE cigarettes that primarily heat tobacco in the SENCAR mouse dermal tumor promotion assay.-

    "..the number of ECLIPSE tumor-bearing animals were reduced 83%, 93% and 67% at the low-, mid- and high-doses, respectively, compared to the 1R4F. Similarly, the total number of dermal tumors was reduced 91%, 94% and 87% at the low-, mid- and high-dose, respectively, compared to the 1R4F CSC. ECLIPSE CSC demonstrated dramatic reductions in dermal tumor promotion potential compared to 1R4F CSC."

    "Reductions in tumor promotion" as compared to the 1R4F....Who wouldn't want that?

    All that they (or any tobacco company for that matter) need to do now is get the taste right, so that current smokers will make the switch. There are also some major hurdles to overcome with regards to free speech and the dissemination of vital information to the public (ie., smokers)at large. How can smokers switch to less risky products if they/we are not allowed to know about them? It's a real conundrum.

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  5. ..and..there already exists the knowledge needed to reduce up to 90% of the carcinogenic nature of COMBUSTIBLE cigarettes:

    http://www.jove.com/about/press-releases/10/researchers-create-healthier-cigarette

    -Researchers Create Healthier Cigarette-

    "Using natural antioxidant extracts in cigarette filters, the researchers were able to demonstrate that lycopene and grape seed extract drastically reduced the amount of cancer-causing free radicals passing through the filter."

    ""The implications of this technique can help reduce the hazardous effects of tobacco smoke," said Dr. Boris Dzilkovski, who co-authored the paper, "because free radicals are a major group of carcinogens.""

    "Scientists have tried to make safer cigarettes in the past. Haemoglobin (which transports oxygen in red blood cells) and activated carbon have been shown to reduce free-radicals in cigarette smoke by up to 90 percent, but because of the cost, the combination has not been successfully introduced to the market."

    ....because of the cost. Nice. I wouldn't mind my tobacco tax dollars going towards this instead toward the ACS (sorry, I don't trust the ACS), would you? I'm all for supporting the scientists.

    ""Practically, this research could lead to an alternative type of cigarette filter with a free radical scavenging additive," said Kolski-Andreaco. "It could lead to a less harmful cigarette.""

    Don't expect to hear about this on the nightly news...not yet anyway.

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  6. Defacto prohibition is quite literally killing people.

    Too much coffee for me today:-)

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